Meal frequency and timing in health and disease
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Periodic fasting and caloric restriction prevent aging and rejuvenate the body – read a new article published in most authoritative and prestigious scientific journal in the world “PNAS“, http://www.ncbi.nlm.nih.gov/pubmed/25404320

Meal frequency and timing in health and disease.
Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16647-53
Mattson MP1, Allison DB2, Fontana L3, Harvie M4, Longo VD5, Malaisse WJ6, Mosley M7, Notterpek L8, Ravussin E9, Scheer FA10, Seyfried TN11, Varady KA12, Panda S13.
Abstract
Although major research efforts have focused on how specific components of foodstuffs affect health, relatively little is known about a more fundamental aspect of diet, the frequency and circadian timing of meals, and potential benefits of intermittent periods with no or very low energy intakes. The most common eating pattern in modern societies, three meals plus snacks every day, is abnormal from an evolutionary perspective. Emerging findings from studies of animal models and human subjects suggest that intermittent energy restriction periods of as little as 16 h can improve health indicators and counteract disease processes. The mechanisms involve a metabolic shift to fat metabolism and ketone production, and stimulation of adaptive cellular stress responses that prevent and repair molecular damage. As data on the optimal frequency and timing of meals crystallizes, it will be critical to develop strategies to incorporate those eating patterns into health care policy and practice, and the lifestyles of the population.


 
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